Nature Medicine, Published online: 05 May 2026; doi:10.1038/s41591-026-04403-9
The agentic artificial intelligence tool SPARK is able to reproduce pathology-based reasoning and produce biological hypotheses and relevant diagnostic, prognostic and predictive cellular parameters. The output of SPARK has the potential to advance the understanding of tumor biology and enable the development of diagnostic, prognostic and predictive tools for pathology and oncology.
