Science News

Meiosis is essential to sexual reproduction. For almost 15 years, it has been commonly held that retinoic acid, a molecule derived from vitamin A, triggers meiosis in mammalian germ cells. Yet, in joint articles published in Science Advances, French researchers from the Institut de Biologie Valrose (CNRS / INSERM / Université Côte d’Azur) and the IGBMC (CNRS / INSERM / University of Strasbourg), with their colleagues, have demonstrated that meiosis in mice begins and proceeds normally even in the absence of retinoic acid. These findings set the stage for new research in the field of reproductive biology.
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