ScienceNews

Science News

Nature Medicine, Published online: 20 April 2026; doi:10.1038/s41591-026-04318-5 Microbiome analysis suggests that gut microbial changes in Parkinson’s disease evolve progressively from healthy individuals to genetically at-risk individuals to clinically affected patients, with the degree of dysbiosis correlating with disease progression. Read More

Science News

Nature Medicine, Published online: 20 April 2026; doi:10.1038/s41591-026-04365-y As presented at the 2026 AACR Annual Meeting, in a phase 2 trial, treatment of patients with high-risk smoldering multiple myeloma with BCMA-targeting CAR T cell therapy ciltacabtagene autoleucel was safe and led to encouraging rates of clinical responses. Read More

Science News

Nature Medicine, Published online: 20 April 2026; doi:10.1038/s41591-026-04380-z As presented at the 2026 AACR Annual Meeting: in a phase 1b trial, patients with microsatellite-stable colorectal cancer received a FAP-4-1BB ligand together with the CEA-directed T cell engager cibisatamab; the treatment was safe, and biomarker analysis showed induction of immunity in line with the biological rationale. …