Nature Medicine, Published online: 21 April 2026; doi:10.1038/s41591-026-04342-5
An analysis of exposome traits in patients with early-onset colorectal cancer (CRC) (<50 years) compared with late-onset CRC (≥70 years) based on epigenetic markers shows that pesticide usage, in particular of picloram, is associated with early-onset CRC.


