Nature Medicine, Published online: 29 October 2026; doi:10.1038/s41591-026-04723-w A 5-year secondary analysis of the phase 2 PHERGain trial supports the clinical utility of a PET-guided adaptive strategy for treatment de-escalation in HER2-positive early breast cancer and provides circulating tumor DNA insights that could inform further treatment approaches. Read More
Nature Medicine, Published online: 29 October 2026; doi:10.1038/d41591-026-00055-x Preclinical analysis and a phase 1 trial support VG-3927 as a promising drug candidate for Alzheimer’s disease, demonstrating successful penetration of the central nervous system, target engagement and tolerability. Read More
Nature Medicine, Published online: 29 October 2026; doi:10.1038/s41591-026-04721-y A high-resolution snRNA-seq atlas of 189 colorectal tumors from patients aged 20–90+ years uncovers age-associated features of colorectal cancer. Read More
Apple has officially introduced the all-new MacBook Pro, marking a major milestone as the company’s first touchscreen Mac. Powered by the M5 Pro and M5 Max chips, this high-end laptop features a completely redesigned, thinner, and lighter form factor alongside cutting-edge display technology. The headline feature is the PROLED XDR display, which replaces previous Mini-LED …
The first estimate of CTE prevalence across the NFL suggests 75 percent of players may suffer from the neurodegenerative disease. Read More